Heritability of myopia and its relation with GDJ2 and RASGRF1 genes in Lithuania.
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ABSTRACT:
SUBMITTER: Kunceviciene E
PROVIDER: S-EPMC5968600 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Publications
Heritability of myopia and its relation with GDJ2 and RASGRF1 genes in Lithuania.
Kunceviciene Edita E Sriubiene Margarita M Liutkeviciene Rasa R Miceikiene Ilona T IT Smalinskiene Alina A
BMC ophthalmology 20180524 1
<h4>Background</h4>This study aimed to assess heritability of myopia in Lithuania and evaluate both genes GJD2 (Gap Junction Protein, Delta 2) and RASGRF1 (RAS protein-specific guanine nucleotide-releasing factor 1) relation with myopia.<h4>Methods</h4>In this study Lithuanian twin population aged between 18 and 40 (n = 460) were examined. Single-nucleotide polymorphisms of the RASGRF1 (rs8027411) and GJD2 (rs634990) genes were assessed by real-time polymerase chain reaction method.<h4>Results</ ...[more]
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