Ontology highlight
ABSTRACT:
SUBMITTER: Otsuka R
PROVIDER: S-EPMC5969074 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Otsuka Ryota R Akutsu Yasunori Y Sakata Haruhito H Hanari Naoyuki N Murakami Kentaro K Kano Masayuki M Toyozumi Takeshi T Takahashi Masahiko M Matsumoto Yasunori Y Sekino Nobufumi N Yokoyama Masaya M Okada Koichiro K Shiraishi Tadashi T Komatsu Aki A Iida Keiko K Matsubara Hisahiro H
Oncology 20171208 3
<h4>Objective</h4>ZNF750, a transcriptional regulator of epidermal differentiation, has been identified as a tumor suppressor in esophageal squamous cell carcinoma (ESCC). The aim of the present study was to investigate the clinical and prognostic significance of ZNF750 expression and to evaluate the effect of ZNF750 knockdown on cell proliferation, migration, and invasion in ESCC.<h4>Methods</h4>A total of 124 patients with ESCC who underwent curative esophagectomy were evaluated in this study. ...[more]