Ontology highlight
ABSTRACT:
SUBMITTER: Fontes-Dutra M
PROVIDER: S-EPMC5972198 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Fontes-Dutra Mellanie M Santos-Terra Júlio J Deckmann Iohanna I Brum Schwingel Gustavo G Della-Flora Nunes Gustavo G Hirsch Mauro Mozael MM Bauer-Negrini Guilherme G Riesgo Rudimar S RS Bambini-Júnior Victorio V Hedin-Pereira Cecília C Gottfried Carmem C
Frontiers in Synaptic Neuroscience 20180522
Autism spectrum disorder (ASD) is characterized by impairments in both social communication and interaction and repetitive or stereotyped behaviors. Although its etiology remains unknown, genetic and environmental risk factors have been associated with this disorder, including the exposure to valproic acid (VPA) during pregnancy. Resveratrol (RSV) is an anti-inflammatory and antioxidant molecule known to prevent social impairments in the VPA animal model of autism. This study aimed to analyze th ...[more]