Ontology highlight
ABSTRACT:
SUBMITTER: Jackson DJ
PROVIDER: S-EPMC5972517 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Jackson Daniel J DJ Bacharier Leonard B LB Mauger David T DT Boehmer Susan S Beigelman Avraham A Chmiel James F JF Fitzpatrick Anne M AM Gaffin Jonathan M JM Morgan Wayne J WJ Peters Stephen P SP Phipatanakul Wanda W Sheehan William J WJ Cabana Michael D MD Holguin Fernando F Martinez Fernando D FD Pongracic Jacqueline A JA Baxi Sachin N SN Benson Mindy M Blake Kathryn K Covar Ronina R Gentile Deborah A DA Israel Elliot E Krishnan Jerry A JA Kumar Harsha V HV Lang Jason E JE Lazarus Stephen C SC Lima John J JJ Long Dayna D Ly Ngoc N Marbin Jyothi J Moy James N JN Myers Ross E RE Olin J Tod JT Raissy Hengameh H HH Robison Rachel G RG Ross Kristie K Sorkness Christine A CA Lemanske Robert F RF
The New England journal of medicine 20180303 10
<h4>Background</h4>Asthma exacerbations occur frequently despite the regular use of asthma-controller therapies, such as inhaled glucocorticoids. Clinicians commonly increase the doses of inhaled glucocorticoids at early signs of loss of asthma control. However, data on the safety and efficacy of this strategy in children are limited.<h4>Methods</h4>We studied 254 children, 5 to 11 years of age, who had mild-to-moderate persistent asthma and had had at least one asthma exacerbation treated with ...[more]