Hepatitis D Viremia Among Injection Drug Users in San Francisco.
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ABSTRACT:
SUBMITTER: Mahale P
PROVIDER: S-EPMC5972608 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Publications
Hepatitis D Viremia Among Injection Drug Users in San Francisco.
Mahale Parag P Aka Peter V PV Chen Xiaohua X Liu Ping P Fram Benjamin J BJ Wang Alan S AS Simenel Scott S Tseng Fan-Chen FC Chen Sabrina S Edlin Brian R BR Glenn Jeffrey S JS O'Brien Thomas R TR
The Journal of infectious diseases 20180501 12
People who inject drugs (PWID) are commonly exposed to hepatitis B virus (HBV) and hepatitis D virus (HDV). We evaluated the prevalence of HDV viremia among hepatitis B surface antigen (HBsAg)-positive PWID (n = 73) using a new quantitative microarray antibody capture (Q-MAC) assay, HDV western blot, and HDV RNA. HDV Q-MAC performed well in this cohort: anti-HDV, 100% sensitivity and specificity; HDV viremia, 61.5% sensitivity and 100% specificity. Hepatitis D viremia was present in 35.6% of HBs ...[more]
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