Ontology highlight
ABSTRACT:
SUBMITTER: Romanov-Michailidis F
PROVIDER: S-EPMC5972829 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Romanov-Michailidis Fedor F Ravetz Benjamin D BD Paley Daniel W DW Rovis Tomislav T
Journal of the American Chemical Society 20180411 16
A novel, electron-deficient cyclopentadienyl iridium(III) catalyst enables sequential cleavage of arene C(sp<sup>2</sup>)-H and methoxy C(sp<sup>3</sup>)-H bonds of anisoles, generating reactive metalacycles that insert difluoroalkynes to afford chromenes under mild reaction conditions. This transformation is an arylalkylation of an alkyne-a carbocarbation-via a nonchelate-assisted cleavage of two C-H bonds. ...[more]