Ontology highlight
ABSTRACT:
SUBMITTER: Van Moerbeke M
PROVIDER: S-EPMC5974242 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Van Moerbeke Marijke M Kasim Adetayo A Shkedy Ziv Z
Scientific reports 20180529 1
Alternative gene splicing is a common phenomenon in which a single gene gives rise to multiple transcript isoforms. The process is strictly guided and involves a multitude of proteins and regulatory complexes. Unfortunately, aberrant splicing events have been linked to genetic disorders. Therefore, understanding mechanisms of alternative splicing regulation and differences in splicing events between diseased and healthy tissues is crucial in advancing personalized medicine and drug developments. ...[more]