Ontology highlight
ABSTRACT:
SUBMITTER: Min JW
PROVIDER: S-EPMC5974623 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Min Jae-Woong JW Koh Youngil Y Kim Dae-Yoon DY Kim Hyung-Lae HL Han Jeong A JA Jung Yu-Jin YJ Yoon Sung-Soo SS Choi Sun Shim SS
Molecules and cells 20180515 5
The advent of massively parallel sequencing, also called next-generation sequencing (NGS), has dramatically influenced cancer genomics by accelerating the identification of novel molecular alterations. Using a whole genome sequencing (WGS) approach, we identified somatic coding and noncoding variants that may contribute to leukemogenesis in 11 adult Korean acute myeloid leukemia (AML) patients, with serial tumor samples (primary and relapse) available for 5 of them; somatic variants were identif ...[more]