Ontology highlight
ABSTRACT:
SUBMITTER: Emenike BU
PROVIDER: S-EPMC5975927 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Emenike Bright U BU Bey Sara N SN Bigelow Brianna C BC Chakravartula Srinivas V S SVS
Chemical science 20151117 2
The strength of CH-aryl interactions (Δ<i>G</i>) in 14 solvents was determined <i>via</i> the conformational analysis of a molecular torsion balance. The molecular balance adopted folded and unfolded conformers in which the ratio of the conformers in solution provided a quantitative measure of Δ<i>G</i> as a function of solvation. While a single empirical solvent parameter based on solvent polarity failed to explain solvent effect in the molecular balance, it is shown that these Δ<i>G</i> values ...[more]