Energy Expenditure in Pregnant Women with Obesity Does Not Support Energy Intake Recommendations.

ABSTRACT: OBJECTIVE:This study aimed to identify factors that may predispose women to excess gestational weight gain (GWG). METHODS:Seventy-two healthy women with obesity (30 class I, 24 class II, 18 class III) expecting a singleton pregnancy were studied at 13 to 16 weeks gestation. Energy expenditure (EE) was measured during sleep (SleepEE, average EE from 0200-0500 hours) in a whole-room calorimeter, and total daily EE (TDEE) over 7 days using doubly labeled water. Glucose, insulin, thyroid hormones, and catecholamines were measured. RESULTS:Body composition explained 70% variability in SleepEE, and SleepEE accounted for 67% to 73% of TDEE. Though there was no evidence of consistent low metabolism, there was considerable variability. Low SleepEE was associated with insulin resistance and low triiodothyronine concentrations (both P?=?0.01). Physical activity level was 1.47?±?0.02. For women with SleepEE within 100 kcal/d of their predicted EE, TDEE was significantly less than the estimate (2,530?±?91 vs. 2,939 kcal/d; P?

SUBMITTER: Most J 

PROVIDER: S-EPMC5978753 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature