Proteomic analysis of plasma extracellular vesicles reveals mitochondrial stress upon HTLV-1 infection.
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ABSTRACT:
SUBMITTER: Jeannin P
PROVIDER: S-EPMC5980083 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
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Proteomic analysis of plasma extracellular vesicles reveals mitochondrial stress upon HTLV-1 infection.
Jeannin Patricia P Chaze Thibault T Giai Gianetto Quentin Q Matondo Mariette M Gout Olivier O Gessain Antoine A Afonso Philippe V PV
Scientific reports 20180326 1
Extracellular vesicles (EVs) can participate in intercellular communication and pathogenesis. EVs contain many cargos, including proteins, and the composition of EVs differs between cell-types and activation levels. Thus, plasma EVs can be used as a biomarker of systemic response to infection and/or disease progression. In this study, we aimed at describing alterations in the protein content of plasma EVs upon infection with the human T-lymphotropic retrovirus type 1 (HTLV-1). HTLV-1 is the etio ...[more]
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