Ontology highlight
ABSTRACT:
SUBMITTER: Arnal G
PROVIDER: S-EPMC5980535 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Arnal Gregory G Cockburn Darrell W DW Brumer Harry H Koropatkin Nicole M NM
Protein science : a publication of the Protein Society 20180417 6
Bacteria that reside in the mammalian intestinal tract efficiently hydrolyze dietary carbohydrates, including starch, that escape digestion in the small intestine. Starch is an abundant dietary carbohydrate comprised of α1,4 and α1,6 linked glucose, yet mammalian intestinal glucoamylases cannot effectively hydrolyze starch that has frequent α1,6 branching as these structures hinder recognition and processing by α1,4-specific amylases. Here we present the structure of the cell surface amylase Sus ...[more]