Ontology highlight
ABSTRACT:
SUBMITTER: Su L
PROVIDER: S-EPMC5982761 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Su Long L Tan YeHui Y Lin Hai H Liu XiaoLiang X Yu Li L Yang YanPing Y Liu ShanShan S Bai Ou O Yang Yan Y Jin FengYan F Sun JingNan J Liu ChunShui C Liu QiuJu Q Gao SuJun S Li Wei W
Oncotarget 20180103 38
The aim of this study was to profile the spectrum of genetic mutations in acute myeloid leukemia (AML) patients co-occurring with <i>CEBPA</i> double mutation (<i>CEBPA</i><sup>dm</sup>). Between January 1, 2012, and June 30, 2017, 553 consecutive patients with <i>de novo</i> AML were screened for <i>CEBPA</i> mutations. Out of these, 81 patients classified as <i>CEBPA</i><sup>dm</sup> were analyzed further by a sensitive next-generation sequencing assay for mutations in 112 candidate genes. Wit ...[more]