Ontology highlight
ABSTRACT: Objective
The purpose of this review was to identify risk factors, prognostic factors, and comorbidities associated with common spinal disorders.Methods
A scoping review of the literature of common spinal disorders was performed through September 2016. To identify search terms, we developed 3 terminology groups for case definitions: 1) spinal pain of unknown origin, 2) spinal syndromes, and 3) spinal pathology. We used a comprehensive strategy to search PubMed for meta-analyses and systematic reviews of case-control studies, cohort studies, and randomized controlled trials for risk and prognostic factors and cross-sectional studies describing associations and comorbidities.Results
Of 3,453 candidate papers, 145 met study criteria and were included in this review. Risk factors were reported for group 1: non-specific low back pain (smoking, overweight/obesity, negative recovery expectations), non-specific neck pain (high job demands, monotonous work); group 2: degenerative spinal disease (workers' compensation claim, degenerative scoliosis), and group 3: spinal tuberculosis (age, imprisonment, previous history of tuberculosis), spinal cord injury (age, accidental injury), vertebral fracture from osteoporosis (type 1 diabetes, certain medications, smoking), and neural tube defects (folic acid deficit, anti-convulsant medications, chlorine, influenza, maternal obesity). A range of comorbidities was identified for spinal disorders.Conclusion
Many associated factors for common spinal disorders identified in this study are modifiable. The most common spinal disorders are co-morbid with general health conditions, but there is a lack of clarity in the literature differentiating which conditions are merely comorbid versus ones that are risk factors. Modifiable risk factors present opportunities for policy, research, and public health prevention efforts on both the individual patient and community levels. Further research into prevention interventions for spinal disorders is needed to address this gap in the literature.
SUBMITTER: Green BN
PROVIDER: S-EPMC5983449 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Green Bart N BN Johnson Claire D CD Haldeman Scott S Griffith Erin E Clay Michael B MB Kane Edward J EJ Castellote Juan M JM Rajasekaran Shanmuganathan S Smuck Matthew M Hurwitz Eric L EL Randhawa Kristi K Yu Hainan H Nordin Margareta M
PloS one 20180601 6
<h4>Objective</h4>The purpose of this review was to identify risk factors, prognostic factors, and comorbidities associated with common spinal disorders.<h4>Methods</h4>A scoping review of the literature of common spinal disorders was performed through September 2016. To identify search terms, we developed 3 terminology groups for case definitions: 1) spinal pain of unknown origin, 2) spinal syndromes, and 3) spinal pathology. We used a comprehensive strategy to search PubMed for meta-analyses a ...[more]