Ontology highlight
ABSTRACT:
SUBMITTER: Abot A
PROVIDER: S-EPMC5985240 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Abot Anne A Lucas Alexandre A Bautzova Tereza T Bessac Arnaud A Fournel Audren A Le-Gonidec Sophie S Valet Philippe P Moro Cédric C Cani Patrice D PD Knauf Claude C
Molecular metabolism 20180131
<h4>Objective</h4>Decreasing duodenal contraction is now considered as a major focus for the treatment of type 2 diabetes. Therefore, identifying bioactive molecules able to target the enteric nervous system, which controls the motility of intestinal smooth muscle cells, represents a new therapeutic avenue. For this reason, we chose to study the impact of oral galanin on this system in diabetic mice.<h4>Methods</h4>Enteric neurotransmission, duodenal contraction, glucose absorption, modification ...[more]