Ontology highlight
ABSTRACT:
SUBMITTER: Dong FN
PROVIDER: S-EPMC5985338 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Dong Frederick N FN Amiri-Yekta Amir A Martinez Guillaume G Saut Antoine A Tek Julie J Stouvenel Laurence L Lorès Patrick P Karaouzène Thomas T Thierry-Mieg Nicolas N Satre Véronique V Brouillet Sophie S Daneshipour Abbas A Hosseini Seyedeh Hanieh SH Bonhivers Mélanie M Gourabi Hamid H Dulioust Emmanuel E Arnoult Christophe C Touré Aminata A Ray Pierre F PF Zhao Haiqing H Coutton Charles C
American journal of human genetics 20180401 4
The multiple morphological abnormalities of the flagella (MMAF) phenotype is among the most severe forms of sperm defects responsible for male infertility. The phenotype is characterized by the presence in the ejaculate of immotile spermatozoa with severe flagellar abnormalities including flagella being short, coiled, absent, and of irregular caliber. Recent studies have demonstrated that MMAF is genetically heterogeneous, and genes thus far associated with MMAF account for only one-third of cas ...[more]