Ontology highlight
ABSTRACT:
SUBMITTER: Martin NT
PROVIDER: S-EPMC5986726 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Martin Nikolas Tim NT Bell John Cameron JC
Molecular therapy : the journal of the American Society of Gene Therapy 20180405 6
Over the last 60 years an eclectic collection of microbes has been tested in a variety of pre-clinical models as anti-cancer agents. At the forefront of this research are a number of virus-based platforms that have shown exciting activity in a variety of pre-clinical models and are collectively referred to as oncolytic viruses. Our true understanding of the potential and limitations of this therapeutic modality has been substantially advanced through clinical studies carried out over the last 25 ...[more]