Tardigrades Use Intrinsically Disordered Proteins to Survive Desiccation.
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ABSTRACT:
SUBMITTER: Boothby TC
PROVIDER: S-EPMC5987194 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Publications
Tardigrades Use Intrinsically Disordered Proteins to Survive Desiccation.
Boothby Thomas C TC Tapia Hugo H Brozena Alexandra H AH Piszkiewicz Samantha S Smith Austin E AE Giovannini Ilaria I Rebecchi Lorena L Pielak Gary J GJ Koshland Doug D Goldstein Bob B
Molecular cell 20170301 6
Tardigrades are microscopic animals that survive a remarkable array of stresses, including desiccation. How tardigrades survive desiccation has remained a mystery for more than 250 years. Trehalose, a disaccharide essential for several organisms to survive drying, is detected at low levels or not at all in some tardigrade species, indicating that tardigrades possess potentially novel mechanisms for surviving desiccation. Here we show that tardigrade-specific intrinsically disordered proteins (TD ...[more]
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