Ontology highlight
ABSTRACT:
SUBMITTER: Koga S
PROVIDER: S-EPMC5987924 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Koga Satoshi S Hozumi Katsuto K Hirano Ken-Ichi KI Yazawa Masaki M Terooatea Tommy T Minoda Aki A Nagasawa Takashi T Koyasu Shigeo S Moro Kazuyo K
The Journal of experimental medicine 20180504 6
Group 2 innate lymphoid cells (ILC2s) are derived from common lymphoid progenitors (CLPs) via several specific precursors, and the transcription factors essential for ILC2 differentiation have been extensively studied. However, the external factors regulating commitment to the ILC lineage as well as the sites and stromal cells that constitute the optimal microenvironment for ILC2-specific differentiation are not fully defined. In this study, we demonstrate that three key external factors, the co ...[more]