MicroRNA-17 and the prognosis of human carcinomas: a systematic review and meta-analysis.

ABSTRACT:

Objective

Although the role of microRNA-17 (miR-17) has been identified as a tumour biomarker in various studies, its prognostic value in cancers remains unclear. Therefore, we performed a systematic review and meta-analysis to analyse and summarise the relationship between the miR-17 status and clinical outcome in a variety of human cancers.

Design

Systematic review and meta-analysis.

Data sources

PubMed, Web of Science and Embase from the first year of records to 15 May 2017.

Outcomes

The patients' survival results were pooled, and pooled HRs with 95% CIs were calculated and used for measuring the strength of association between miR-17 and the prognosis of cancers, including hepatocellular carcinoma, lung cancer, osteosarcoma, glioma, T-cell lymphoblastic lym

SUBMITTER: Huang C 

PROVIDER: S-EPMC5988052 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature