Ontology highlight
ABSTRACT:
SUBMITTER: Giallourou N
PROVIDER: S-EPMC5988333 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Giallourou Natasa N Medlock Gregory L GL Bolick David T DT Medeiros Pedro Hqs PH Ledwaba Solanka E SE Kolling Glynis L GL Tung Kenneth K Guerry Patricia P Swann Jonathan R JR Guerrant Richard L RL
PLoS pathogens 20180301 3
Campylobacter infections are among the leading bacterial causes of diarrhea and of 'environmental enteropathy' (EE) and growth failure worldwide. However, the lack of an inexpensive small animal model of enteric disease with Campylobacter has been a major limitation for understanding its pathogenesis, interventions or vaccine development. We describe a robust standard mouse model that can exhibit reproducible bloody diarrhea or growth failure, depending on the zinc or protein deficient diet and ...[more]