Ontology highlight
ABSTRACT:
SUBMITTER: Catterson JH
PROVIDER: S-EPMC5988561 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Catterson James H JH Khericha Mobina M Dyson Miranda C MC Vincent Alec J AJ Callard Rebecca R Haveron Steven M SM Rajasingam Arjunan A Ahmad Mumtaz M Partridge Linda L
Current biology : CB 20180517 11
Intermittent fasting (IF) can improve function and health during aging in laboratory model organisms, but the mechanisms at work await elucidation. We subjected fruit flies (Drosophila melanogaster) to varying degrees of IF and found that just one month of a 2-day fed:5-day fasted IF regime at the beginning of adulthood was sufficient to extend lifespan. This long-lasting, beneficial effect of early IF was not due to reduced fecundity. Starvation resistance and resistance to oxidative and xenobi ...[more]