Ontology highlight
ABSTRACT:
SUBMITTER: Roycroft A
PROVIDER: S-EPMC5988567 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Roycroft Alice A Szabó András A Bahm Isabel I Daly Liam L Charras Guillaume G Parsons Maddy M Mayor Roberto R
Developmental cell 20180601 5
Contact inhibition of locomotion is defined as the behavior of cells to cease migrating in their former direction after colliding with another cell. It has been implicated in multiple developmental processes and its absence has been linked to cancer invasion. Cellular forces are thought to govern this process; however, the exact role of traction through cell-matrix adhesions and tension through cell-cell adhesions during contact inhibition of locomotion remains unknown. Here we use neural crest ...[more]