Ontology highlight
ABSTRACT:
SUBMITTER: Shen T
PROVIDER: S-EPMC5988606 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Shen Ting T You Yuyi Y Joseph Chitra C Mirzaei Mehdi M Klistorner Alexander A Graham Stuart L SL Gupta Vivek V
Aging and disease 20180601 3
Brain-derived neurotrophic factor (BDNF) has a unique role in the neuronal development, differentiation, and survival in the developing and adult nervous system. A common single-nucleotide polymorphism in the pro-region of the human BDNF gene, resulting in a valine to methionine substitution (Val66Met), has been associated with the susceptibility, incidence, and clinical features of several neurodegenerative disorders. Much research has been dedicated to evaluating the effects of polymorphism in ...[more]