Multimorbidity Analysis According to Sex and Age towards Cardiovascular Diseases of Adults in Northeast China.
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ABSTRACT:
SUBMITTER: Jin L
PROVIDER: S-EPMC5988667 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Publications
Multimorbidity Analysis According to Sex and Age towards Cardiovascular Diseases of Adults in Northeast China.
Jin Lina L Guo Xin X Dou Jing J Liu Binghui B Wang Jiangzhou J Li Jiagen J Sun Mengzi M Sun Chong C Yu Yaqin Y Yao Yan Y
Scientific reports 20180605 1
Non-communicable diseases (NCDs) are great challenges in public health, where cardiovascular diseases (CVD) accounted for the large part of mortality that caused by NCDs. Multimorbidity is very common in NCDs especially in CVD, thus multimorbidity could make NCDs worse and bring heavy economic burden. This study aimed to explore the multimorbidity among adults, especially the important role of CVD that played in the entire multimorbidity networks. A total of 21435 participants aged 18-79 years o ...[more]
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| S-EPMC7277827 | biostudies-literature
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| S-EPMC10941372 | biostudies-literature
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| S-EPMC10724809 | biostudies-literature
Project description:BackgroundThe distribution of allergens has geographic characteristics. Local epidemiological data provides evidence-based strategies for the prevention and management of allergic diseases. Age and sex differences may exist in the prevalence of sensitivity to various allergens. We investigated the distribution of common allergens in allergic children in Shanghai, southeastern China.Methods39,926 children 1 month to 18 years of age diagnosed with allergic diseases were tested for the presence of serum-specific Immunoglobulins E (sIgE) to 17 allergens common to this region, using a reversed enzyme allergosorbent test.Results25,757 (64.5%) of the subjects showed elevated sIgE to at least one of the tested allergens. House mite and dust mite were the most common aeroallergens, while egg and milk were the most common food allergens. The most common aeroallergens and food allergens were similar among each allergic disease. By age-group analysis, the positive rates of aeroallergens were higher at older age. Several peaks of sensitization to food allergens were observed in children between 1 and 3 years of age for eggs, milk, nut, crab and shrimp. In addition, the sensitization to beef and mango was highest in children 3-6 years of age. The rate of positive sIgE detection was higher in males than females for all the tested allergens except cockroach, trees and beef. Considering the interplay between sex and ages and other related components (including season, monthly temperature, humidity, air quality index, test rate of patients), the sIgE positive rates of the main aeroallergens increased with age, while the main food allergens decreased; males are more sensitive to several aeroallergens (including dust mite, house mite, cat epithelium, dog epithelium and mulberry).ConclusionsHouse mite, dust mite, milk, and egg are major allergens in Shanghai. Children at younger age are more sensitive to food allergens, while increasing overall prevalence of sensitization can be found with increasing age. Boys have higher positive rates of sIgE responses than girls. Knowledge of the prevalence of allergen sensitization in different age groups and sex may help facilitate diagnosis and intervention efforts to mitigate the impact of allergic diseases in this large geographical region. This approach may be extrapolated to other regions.
| S-EPMC9013110 | biostudies-literature
Project description:ObjectivesThis study aimed to identify and study the associations and co-occurrence of multimorbidity, and assessed the associations of diseases with sex, age and hospitalisation duration.DesignCross-sectional.Setting15 general hospitals in Jilin Province, China.ParticipantsA total of 431 295 inpatients were enrolled through a cross-sectional study in Jilin Province, China.Primary outcome measuresThe complex relationships of multimorbidity were presented as weighted networks.ResultsThe distributions of the numbers of diseases differed significantly by sex, age and hospitalisation duration (p<0.001). Cerebrovascular diseases (CD), hypertensive diseases (HyD), ischaemic heart diseases (IHD) and other forms of heart disease (OFHD) showed the highest weights in the multimorbidity networks. The connections between different sexes or hospitalisation duration and diseases were similar, while those between different age groups and diseases were different.ConclusionsCD, HyD, IHD and OFHD were the central points of disease clusters and directly or indirectly related to other diseases or factors. Thus, effective interventions for these diseases should be adopted. Furthermore, different intervention strategies should be developed according to multimorbidity patterns in different age groups.
| S-EPMC8572406 | biostudies-literature