Dataset Information

Factors associated with late presentation for HIV care in a single Belgian reference center: 2006-2017.

ABSTRACT: Late presentation for HIV care is a major issue and the cause of higher morbidity, mortality and transmission. In this regard, we analyzed the characteristics of patients presenting for care at our center from January 2006 to July 2017 (n?=?687). The majority of the studied population was of African origin (54.3%) with heterosexual women representing the main group (n?=?292; 42.5%). 44% of the patients were late presenters (LP) (presenting for care with CD4 T cells <350/mm3 or an AIDS defining event) and 24% were late presenters with advanced disease (LP-AD) (presenting for care with CD4 T cells <200/mm3 or an AIDS defining event). A very high risk of being LP and LP-AD was associated with Sub-Saharan origin (OR 3.4 and 2.6 respectively). Other factors independently associated with LP or LP-AD were age (OR 1.3), male gender (OR 2.0 and 1.5 respectively) and heterosexual route of transmission (OR 2.4 and 2.3 respectively). A significant increase in HIV screening without forgetting those groups would contribute to earlier HIV diagnosis, a key element to end the HIV epidemic. To achieve this goal, addressing the specific hurdles to HIV testing in the migrant population is critical.

SUBMITTER: Darcis G

PROVIDER: S-EPMC5988738 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Factors associated with late presentation for HIV care in a single Belgian reference center: 2006-2017.

Darcis Gilles G Lambert Iseult I Sauvage Anne-Sophie AS Frippiat Frédéric F Meuris Christelle C Uurlings Françoise F Lecomte Marianne M Léonard Philippe P Giot Jean-Baptiste JB Fombellida Karine K Vaira Dolores D Moutschen Michel M

Scientific reports 20180605 1

Late presentation for HIV care is a major issue and the cause of higher morbidity, mortality and transmission. In this regard, we analyzed the characteristics of patients presenting for care at our center from January 2006 to July 2017 (n = 687). The majority of the studied population was of African origin (54.3%) with heterosexual women representing the main group (n = 292; 42.5%). 44% of the patients were late presenters (LP) (presenting for care with CD4 T cells <350/mm<sup>3</sup> or an AIDS ...[more]

PMID: 29872068

Similar Datasets

Project description:IntroductionLate presentation to HIV/AIDS care which is attended by problems like, poor treatment outcomes, early development of opportunistic infections, increased healthcare costs, and mortality is a major problem in Ethiopia. Although evidences are available on the prevalence and associated factors of late presentation to HIV/AIDS care, discrepancies among findings are appreciated. Thus, the country has faced difficulties of having a single estimated data.ObjectiveThis study aimed to estimate the pooled prevalence of late presentation of HIV positive adults to HIV/AIDS care and its predictors in Ethiopia.MethodWe searched all available articles through Google Scholar, PubMed, Web of Sciences, and EMBASE databases. Additionally, we accessed articles from the Ethiopian institutional online research repositories and reference lists of included studies. We included cohort, case- control, and cross-sectional studies in our review. Besides, we utilized the weighted inverse variance random-effects model. The total percentage of variation among studies due to heterogeneity was determined by I2 statistic. Searching was limited to studies conducted in Ethiopia and published in the English language. Publication bias was checked by Egger's regression test.ResultsA total of 8 studies with 7, 568 participants were included. The pooled prevalence of late presentation to HIV/AIDS care was 52.89% (95%CI: 35.37, 70.40). The odds of late presentation to HIV/AIDS care of frequent alcohol users [3.67(95% CI?=?1.52-5.83)], high fear of stigma [3.90 (95% CI?=?1.51-6.28)], chronic illness [3.34(95% CI?=?1.52-5.16)], and the presence of symptoms at the time of HIV diagnosis [3.06 (95% CL?=?1.18-4.94)] were higher compared to participants who did not experience the preceding.ConclusionThe prevalence of late presentation of HIV positive adults to HIV/AIDS care was high in Ethiopia. Frequent alcohol use, high fear of stigma, chronic illness, and the presence of symptoms at the time of HIV diagnosis were associated with high odds of late presentation to HIV/AIDS care.Trial registrationRegistered in PROSPERO databases with the registration number of CRD42018081840 .

Dataset Information

Factors associated with late presentation for HIV care in a single Belgian reference center: 2006-2017.

Publications

Factors associated with late presentation for HIV care in a single Belgian reference center: 2006-2017.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets