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Reduced structural connectivity in ventral visual cortex in congenital prosopagnosia.

ABSTRACT: Using diffusion tensor imaging and tractography, we found that a disruption in structural connectivity in ventral occipito-temporal cortex may be the neurobiological basis for the lifelong impairment in face recognition that is experienced by individuals who suffer from congenital prosopagnosia. Our findings suggest that white-matter fibers in ventral occipito-temporal cortex support the integrated function of a distributed cortical network that subserves normal face processing.

SUBMITTER: Thomas C

PROVIDER: S-EPMC5989137 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature

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Reduced structural connectivity in ventral visual cortex in congenital prosopagnosia.

Thomas Cibu C Avidan Galia G Humphreys Kate K Jung Kwan-jin KJ Gao Fuqiang F Behrmann Marlene M

Nature neuroscience 20081123 1

Using diffusion tensor imaging and tractography, we found that a disruption in structural connectivity in ventral occipito-temporal cortex may be the neurobiological basis for the lifelong impairment in face recognition that is experienced by individuals who suffer from congenital prosopagnosia. Our findings suggest that white-matter fibers in ventral occipito-temporal cortex support the integrated function of a distributed cortical network that subserves normal face processing. ...[more]

PMID: 19029889

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