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Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus.


ABSTRACT: Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections.

SUBMITTER: Li S 

PROVIDER: S-EPMC5990757 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature

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Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant <i>Staphylococcus aureus</i>.

Li Shuihong S   Mou Qianqian Q   Xu Xinya X   Qi Shuhua S   Leung Polly H M PHM  

Royal Society open science 20180530 5


Penicillenol A2 (isolated from deep-sea fungus <i>Penicillium biourgeianum</i> DFFSCS023) has good antibacterial activity against methicillin-sensitive <i>Staphylococcus aureus</i> and in combination with <i>beta</i>-lactam antibiotics it could significantly decrease methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections. ...[more]

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