Ontology highlight
ABSTRACT:
SUBMITTER: Muller JA
PROVIDER: S-EPMC5992203 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Müller Janis A JA Harms Mirja M Krüger Franziska F Groß Rüdiger R Joas Simone S Hayn Manuel M Dietz Andrea N AN Lippold Sina S von Einem Jens J Schubert Axel A Michel Manuela M Mayer Benjamin B Cortese Mirko M Jang Karen S KS Sandi-Monroy Nathallie N Deniz Miriam M Ebner Florian F Vapalahti Olli O Otto Markus M Bartenschlager Ralf R Herbeuval Jean-Philippe JP Schmidt-Chanasit Jonas J Roan Nadia R NR Münch Jan J
Nature communications 20180607 1
Zika virus (ZIKV) causes severe birth defects and can be transmitted via sexual intercourse. Semen from ZIKV-infected individuals contains high viral loads and may therefore serve as an important vector for virus transmission. Here we analyze the effect of semen on ZIKV infection of cells and tissues derived from the anogenital region. ZIKV replicates in all analyzed cell lines, primary cells, and endometrial or vaginal tissues. However, in the presence of semen, infection by ZIKV and other flav ...[more]