Ontology highlight
ABSTRACT:
SUBMITTER: Mohamad O
PROVIDER: S-EPMC5993514 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Mohamad Osama O Diaz de Leon Alberto A Schroeder Samuel S Leiker Andrew A Christie Alana A Zhang-Velten Elizabeth E Trivedi Lakshya L Khan Saad S Desai Neil B NB Laine Aaron A Albuquerque Kevin K Iyengar Puneeth P Arriaga Yull Y Courtney Kevin K Gerber David E DE Hammers Hans H Choy Hak H Timmerman Robert R Brugarolas James J Hannan Raquibul R
Oncoimmunology 20180315 7
Integration of hypofractionated body radiotherapy (H-RT) into immune checkpoint inhibitor (ICI) therapy may be a promising strategy to improve the outcomes of ICIs, although sufficient data is lacking regarding the safety and efficacy of this regimen. We, hereby, reviewed the safety and efficacy of this combination in 59 patients treated with H-RT during or within 8 weeks of ICI infusion and compared results with historical reports of ICI treatment alone. Most patients had RCC or melanoma. Media ...[more]