Association of positive well-being with reduced cardiac repolarization abnormalities in the First National Health and Nutrition Examination Survey.

ABSTRACT: BACKGROUND:The mechanisms by which psychological factors may influence possibly arrhythmia risk are not known. We hypothesized that psychological wellness, measured by the General Well-Being Schedule (GBWS), is associated with less repolarization heterogeneity as measured by T-axis. We also explored whether T-axis was a mediator in the relationship of GWBS with adverse cardiac outcomes. METHODS:We studied 5533 adults aged 25-74?years without a history of CVD from NHANES I (National Health and Nutrition Examination Survey) (1971-75). Frontal T-axis was obtained through 12-lead ECG and characterized as normal (15° to 75°), borderline (-15° to 15° or 75° to 105°) or abnormal (>105° or <-15°). RESULTS:The mean?±?SD age was 43.1?±?11.5?years and 55% were women. A 1-SD increase in GWBS score associated with a 23% reduced odds of abnormal T-axis (p?

SUBMITTER: Isakadze N 

PROVIDER: S-EPMC5994381 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature