Analysis of protein-protein interaction network based on transcriptome profiling of ovine granulosa cells identifies candidate genes in cyclic recruitment of ovarian follicles.
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ABSTRACT:
SUBMITTER: Talebi R
PROVIDER: S-EPMC5994657 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
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Analysis of protein-protein interaction network based on transcriptome profiling of ovine granulosa cells identifies candidate genes in cyclic recruitment of ovarian follicles.
Talebi Reza R Ahmadi Ahmad A Afraz Fazlollah F
Journal of animal science and technology 20180611
After pubertal, cohort of small antral follicles enters to gonadotrophin-sensitive development, called recruited follicles. This study was aimed to identify candidate genes in follicular cyclic recruitment via analysis of protein-protein interaction (PPI) network. Differentially expressed genes (DEGs) in ovine granulosa cells of small antral follicles between follicular and luteal phases were accumulated among gene/protein symbols of the Ensembl annotation. Following directed graphs, <i>PTPN6</i ...[more]
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