Hypercapnia does not shorten emergence time from propofol anesthesia: a pilot randomized clinical study.

ABSTRACT:

Background

The elimination of anesthetic agents is a decisive factor in the emergence from general anesthesia. In this pilot study, we hypothesized that hypercapnia would decrease the emergence time from propofol anesthesia by increasing cardiac output and cerebral blood flow.

Methods

A total of 32 patients were randomly divided into two groups based on the end-tidal carbon dioxide values: 30 mmHg (the hypocapnia group) and 50 mmHg (the hypercapnia group). Propofol and remifentanil were infused to maintain a bispectral index of 40-50. Remifentanil infusion was stopped 10 min before the discontinuation of propofol. After cessation of propofol infusion, ventilation settings in the hypocapnia group were maintained constant; a rebreathing tube was connected to the respiratory ci

SUBMITTER: Kwon KH 

PROVIDER: S-EPMC5995009 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature