Ontology highlight
ABSTRACT:
SUBMITTER: Liu Y
PROVIDER: S-EPMC5995387 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Liu Yixin Y Kaljunen Heidi H Pavić Ana A Saarenpää Tuulia T Himanen Juha P JP Nikolov Dimitar B DB Goldman Adrian A
PloS one 20180611 6
Eph/Ephrin signaling pathways are crucial in regulating a large variety of physiological processes during development, such as cell morphology, proliferation, migration and axonal guidance. EphrinA (efn-A) ligands, in particular, can be activated by EphA receptors at cell-cell interfaces and have been proposed to cause reverse signaling via RET receptor tyrosine kinase. Such association has been reported to mediate spinal motor axon navigation, but conservation of the interactive signaling pathw ...[more]