Ontology highlight
ABSTRACT:
SUBMITTER: Suzuki Y
PROVIDER: S-EPMC5995841 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Suzuki Yusuke Y Ii Masaaki M Saito Takashi T Terai Yoshito Y Tabata Yasuhiko Y Ohmichi Masahide M Asahi Michio M
Scientific reports 20180611 1
Uterine leiomyoma is the most common benign tumour in women, and an appropriate animal model for leiomyoma would be useful for exploring new therapeutic strategies. Therefore, we have been challenged to develop a new simple mouse model for human leiomyoma. Leiomyoma tissues were harvested from myomas resected by different surgical procedures with or without gonadotropin-releasing hormone agonist (GnRHa) treatment and were subcutaneously implanted into BALB/c nude mice with an estradiol/progester ...[more]