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Data from a targeted proteomics approach to discover biomarkers in saliva for the clinical diagnosis of periodontitis.

ABSTRACT: This study focused on the search for new biomarkers based on liquid chromatography-multiple reaction monitoring (LC-MRM) proteomics profiling of whole saliva from patients with periodontitis compared to healthy subjects. The LC-MRM profiling approach is a new and innovative method that has already been validated for the absolute and multiplexed quantification of biomarkers in several diseases. The dataset for this study was produced using LC-MRM to monitor protein levels in a multiplex assay, it provides clinical information on salivary biomarkers of periodontitis. The data presented here is an extension of our recently published research article (Mertens et al., 2017) [1].

SUBMITTER: Orti V

PROVIDER: S-EPMC5996262 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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Data from a targeted proteomics approach to discover biomarkers in saliva for the clinical diagnosis of periodontitis.

Orti V V Mertens B B Vialaret J J Gibert P P Relaño-Ginés A A Lehmann S S Deville de Périère D D Hirtz C C

Data in brief 20180312

This study focused on the search for new biomarkers based on liquid chromatography-multiple reaction monitoring (LC-MRM) proteomics profiling of whole saliva from patients with periodontitis compared to healthy subjects. The LC-MRM profiling approach is a new and innovative method that has already been validated for the absolute and multiplexed quantification of biomarkers in several diseases. The dataset for this study was produced using LC-MRM to monitor protein levels in a multiplex assay, it ...[more]

PMID: 29900194

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