Prenatal iron exposure and childhood type 1 diabetes.
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ABSTRACT:
SUBMITTER: Stordal K
PROVIDER: S-EPMC5998022 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Publications
Prenatal iron exposure and childhood type 1 diabetes.
Størdal Ketil K McArdle Harry J HJ Hayes Helen H Tapia German G Viken Marte K MK Lund-Blix Nicolai A NA Haugen Margaretha M Joner Geir G Skrivarhaug Torild T Mårild Karl K Njølstad Pål R PR Eggesbø Merete M Mandal Siddhartha S Page Christian M CM London Stephanie J SJ Lie Benedicte A BA Stene Lars C LC
Scientific reports 20180613 1
Iron overload due to environmental or genetic causes have been associated diabetes. We hypothesized that prenatal iron exposure is associated with higher risk of childhood type 1 diabetes. In the Norwegian Mother and Child cohort study (n = 94,209 pregnancies, n = 373 developed type 1 diabetes) the incidence of type 1 diabetes was higher in children exposed to maternal iron supplementation than unexposed (36.8/100,000/year compared to 28.6/100,000/year, adjusted hazard ratio 1.33, 95%CI: 1.06-1. ...[more]
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