Ontology highlight
ABSTRACT:
SUBMITTER: Agersborg S
PROVIDER: S-EPMC5999182 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Agersborg Sally S Mixon Christopher C Nguyen Thanh T Aithal Sramila S Sudarsanam Sucha S Blocker Forrest F Weiss Lawrence L Gasparini Robert R Jiang Shiping S Chen Wayne W Hess Gregory G Albitar Maher M
Breast cancer research and treatment 20180322 2
<h4>Purpose</h4>While HER2 testing is well established in directing appropriate treatment for breast cancer, a small percentage of cases show equivocal results by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). Alternative probes may be used in equivocal cases. We present a single community-based institution's experience in further evaluating these cases.<h4>Patients and methods</h4>Between 2014 and 2016, 4255 samples were submitted for HER2 amplification testing by alt ...[more]