Data on environmentally relevant level of aflatoxin B1-induced human dendritic cells' functional alteration.
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ABSTRACT:
SUBMITTER: Mehrzad J
PROVIDER: S-EPMC5999520 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Publications
Data on environmentally relevant level of aflatoxin B<sub>1</sub>-induced human dendritic cells' functional alteration.
Mehrzad Jalil J Bahari Abbas A Bassami Mohammad Reza MR Mahmoudi Mahmoud M Dehghani Hesam H
Data in brief 20180430
We assessed the effects of naturally occurring levels of AFB<sub>1</sub> on the expression of key immune molecules and function of human monocyte-derived dendritic cells (MDDCs) by cell culture, RT-qPCR, and flow cytometry. Data here revealed that an environmentally relevant level of AFB<sub>1</sub> led to remarkably weakened key functional capacity of DCs, up-regulation of key transcripts and DCs apoptosis, down-regulation of key phagocytic element, CD64, and creation of pseudolicensing directi ...[more]
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