Trimester-specific phthalate concentrations and glucose levels among women from a fertility clinic.

ABSTRACT: BACKGROUND:Subfertile women are at increased risk of glucose intolerance in pregnancy. Based on epidemiologic studies, exposure to certain phthalates is associated with diabetes, elevated glucose, and increased insulin resistance. OBJECTIVES:To evaluate the association between urinary phthalate metabolites and pregnancy glucose levels in women seeking medically assisted reproduction. METHODS:We evaluated 245 women participating in a prospective cohort study based at a large fertility clinic who delivered live births and had data on pregnancy urinary phthalate metabolite concentrations and blood glucose levels. Urinary phthalate metabolite concentrations were from single spot urine samples collected in 1st and 2nd trimesters. Blood glucose data was abstracted from medical records for non-fa

SUBMITTER: James-Todd TM 

PROVIDER: S-EPMC6000948 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature