Ontology highlight
ABSTRACT:
SUBMITTER: Hosoda Y
PROVIDER: S-EPMC6004488 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20180529 24
Central serous chorioretinopathy (CSC) is a common disease affecting younger people and may lead to vision loss. CSC shares phenotypic overlap with age-related macular degeneration (AMD). As recent studies have revealed a characteristic increase of choroidal thickness in CSC, we conducted a genome-wide association study on choroidal thickness in 3,418 individuals followed by TaqMan assays in 2,692 subjects, and we identified two susceptibility loci: <i>CFH</i> rs800292, an established AMD suscep ...[more]