Ontology highlight
ABSTRACT:
SUBMITTER: Bouchez V
PROVIDER: S-EPMC6004856 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Bouchez Valérie V Guglielmini Julien J Dazas Mélody M Landier Annie A Toubiana Julie J Guillot Sophie S Criscuolo Alexis A Brisse Sylvain S
Emerging infectious diseases 20180601 6
Bordetella pertussis causes whooping cough, a highly contagious respiratory disease that is reemerging in many world regions. The spread of antigen-deficient strains may threaten acellular vaccine efficacy. Dynamics of strain transmission are poorly defined because of shortcomings in current strain genotyping methods. Our objective was to develop a whole-genome genotyping strategy with sufficient resolution for local epidemiologic questions and sufficient reproducibility to enable international ...[more]