Ontology highlight
ABSTRACT:
SUBMITTER: Johnson AC
PROVIDER: S-EPMC6005767 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Johnson Abbie C AC Cipolla Marilyn J MJ
Microvascular research 20180426
Preeclampsia (PE), a dangerous hypertensive complication of pregnancy, is associated with widespread maternal vascular dysfunction. However, the effect of PE on the cerebral vasculature that can lead to stroke and cognitive decline is not well understood. We hypothesized that function of cortical parenchymal arterioles (PAs) would be impaired during PE. Using a high cholesterol diet to induce experimental PE in rats (ePE), we studied the function and structure of isolated and pressurized PAs sup ...[more]