Ontology highlight
ABSTRACT:
SUBMITTER: Zhang J
PROVIDER: S-EPMC6006175 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Zhang Jingru J Wang Yingqiao Y Wang Jianxiang J Hu Jianda J Chen Suning S Jin Jie J Liu Ting T Zhou Jianfeng J Hu Yu Y Ma Daoxin D Huang Xiaojun X Ji Chunyan C Hou Ming M
Blood cancer journal 20180615 7
An early molecular response is spectacularly predictive of outcome in chronic myeloid leukemia (CML) and early response landmarks may identify the high-risk patients likely to be benefit from an early therapy switch. In this study, we evaluated the most relevant cutoffs for early molecular response markers (BCR-ABL1 values at 3 months, log reduction and halving time between diagnosis and 3 months) in 476 first-line imatinib-treated Chinese patients with chronic phase CML. All outcomes were signi ...[more]