Ontology highlight
ABSTRACT:
SUBMITTER: Krause-Kyora B
PROVIDER: S-EPMC6008052 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Krause-Kyora Ben B Susat Julian J Key Felix M FM Kühnert Denise D Bosse Esther E Immel Alexander A Rinne Christoph C Kornell Sabin-Christin SC Yepes Diego D Franzenburg Sören S Heyne Henrike O HO Meier Thomas T Lösch Sandra S Meller Harald H Friederich Susanne S Nicklisch Nicole N Alt Kurt W KW Schreiber Stefan S Tholey Andreas A Herbig Alexander A Nebel Almut A Krause Johannes J
eLife 20180510
The hepatitis B virus (HBV) is one of the most widespread human pathogens known today, yet its origin and evolutionary history are still unclear and controversial. Here, we report the analysis of three ancient HBV genomes recovered from human skeletons found at three different archaeological sites in Germany. We reconstructed two Neolithic and one medieval HBV genome by <i>de novo</i> assembly from shotgun DNA sequencing data. Additionally, we observed HBV-specific peptides using paleo-proteomic ...[more]