Ontology highlight
ABSTRACT:
SUBMITTER: Nan L
PROVIDER: S-EPMC6008937 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Nan Liangliang L Liu Yunchao Y Ji Pengchao P Feng Hua H Chen Chen C Wang Juan J Liu Dongmin D Cui Yinglei Y Wang Yanwei Y Li Yafei Y Zhou Enmin E Zhang Gaiping G
Virology journal 20180619 1
Canine parvovirus (CPV) has been considered to be an important pathogen, which can cause acute infectious disease in canids. Although current vaccines are effective in preventing CPV infection, safety problems still remain unsolved. In this study, a subunit vaccine against CPV based on virus-like particles (VLPs) with good safety and immunogenicity is reported. Soluble CPV VP2 protein was produced by co-expression of chaperone trigger factor (Tf16) in Escherichia coli (E.coli), and assembled int ...[more]