Genetic Diversity of Cryptosporidium hominis in a Bangladeshi Community as Revealed by Whole-Genome Sequencing.
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ABSTRACT:
SUBMITTER: Gilchrist CA
PROVIDER: S-EPMC6009673 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Publications
Genetic Diversity of Cryptosporidium hominis in a Bangladeshi Community as Revealed by Whole-Genome Sequencing.
Gilchrist Carol A CA Cotton James A JA Burkey Cecelia C Arju Tuhinur T Gilmartin Allissia A Lin Ye Y Ahmed Emtiaz E Steiner Kevin K Alam Masud M Ahmed Shahnawaz S Robinson Guy G Zaman Sultan Uz SU Kabir Mamun M Sanders Mandy M Chalmers Rachel M RM Ahmed Tahmeed T Ma Jennie Z JZ Haque Rashidul R Faruque Abu S G ASG Berriman Matthew M Petri William A WA
The Journal of infectious diseases 20180601 2
We studied the genetic diversity of Cryptosporidium hominis infections in slum-dwelling infants from Dhaka over a 2-year period. Cryptosporidium hominis infections were common during the monsoon, and were genetically diverse as measured by gp60 genotyping and whole-genome resequencing. Recombination in the parasite was evidenced by the decay of linkage disequilibrium in the genome over <300 bp. Regions of the genome with high levels of polymorphism were also identified. Yet to be determined is i ...[more]
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