Ontology highlight
ABSTRACT:
SUBMITTER: Tatara AM
PROVIDER: S-EPMC6009980 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Tatara Alexander M AM Rozich Allison J AJ Kontoyiannis Panayiotis D PD Watson Emma E Albert Nathaniel D ND Bennett George N GN Mikos Antonios G AG
Journal of materials science. Materials in medicine 20180511 5
While antibiotic-eluting polymethylmethacrylate space maintainers have shown efficacy in the treatment of bacterial periprosthetic joint infection and osteomyelitis, antifungal-eluting space maintainers are associated with greater limitations for treatment of fungal musculoskeletal infections including limited elution concentration and duration. In this study, we have designed a porous econazole-eluting space maintainer capable of greater inhibition of fungal growth than traditional solid space ...[more]