Ontology highlight
ABSTRACT:
SUBMITTER: Beer B
PROVIDER: S-EPMC6011931 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Microbial biotechnology 20180426 4
Rare sugars and sugar derivatives that can be obtained from abundant sugars are of great interest to biochemical and pharmaceutical research. Here, we describe the substrate scope of a short-chain dehydrogenase/reductase from Sphingomonas species A1 (SpsADH) in the oxidation of aldonates and polyols. The resulting products are rare uronic acids and rare sugars respectively. We provide insight into the substrate recognition of SpsADH using kinetic analyses, which show that the configuration of th ...[more]