Ontology highlight
ABSTRACT:
SUBMITTER: Fu JF
PROVIDER: S-EPMC6014591 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Fu Jessie Fanglu JF Klyuzhin Ivan I Liu Shuying S Shahinfard Elham E Vafai Nasim N McKenzie Jessamyn J Neilson Nicole N Mabrouk Rostom R Sacheli Matthew A MA Wile Daryl D McKeown Martin J MJ Stoessl A Jon AJ Sossi Vesna V
NeuroImage. Clinical 20180521
We used positron emission tomography imaging with [<sup>11</sup>C]-3-amino-4-(2-dimethylaminomethylphenylsulfanyl)- benzonitrile (DASB) and principal component analysis to investigate whether a specific Parkinson's disease (PD)-related spatial covariance pattern could be identified for the serotonergic system. We also explored if non-manifesting leucine-rich repeat kinase 2 (LRRK2) mutation carriers, with normal striatal dopaminergic innervation as measured with [<sup>11</sup>C]-dihydrotetrabena ...[more]